For that mate with whom you have the best banter.
He's your average desk jockey, the guy you pass in the hallway everyday. His work is no better than yours, he's just another Keyboard-Slinging Sam. See also Office.
For those naggy and annoying siblings, classmates, spouses, etc.
For when somebody is being a nag.
Yoo-hoooo! Be a doll and add a funny nickname.
Classic, brother-bestowed nickname for long-suffering sisters named Elizabeth. See, for example, the comic strip For Better or Worse. See also Sophomoric.